Beilstein J. Org. Chem.2018,14, 1508–1528, doi:10.3762/bjoc.14.128
products 46 resulting from a 1,2-benzoyloxyiodination and isolated with moderate to excellent yields (Scheme 15). The reaction is believed to take place through the formation of a hypoiodous species that activates the olefin via an iodonium intermediate.
Tandem catalytic couplings
Diaryliodoniumcompounds
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Graphical Abstract
Scheme 1:
Strategies to address the issue of sustainability with polyvalent organoiodine reagents.
Beilstein J. Org. Chem.2011,7, 1108–1114, doi:10.3762/bjoc.7.127
different reactions can be carried out successfully using simple protocols.
Keywords: diaryliodoniumcompounds; electrochemistry; flow chemistry; microreactor; Introduction
Electrochemical reactions offer a clean route to the formation of anion and cation radical species from neutral organic molecules
the continuous synthesis of diaryliodoniumcompounds. A microflow electrochemical reactor made out of two aluminium bodies (50 mm diameter, 25 mm height) was manufactured. The electrodes are constructed of two PTFE plates (35 mm diameter, 4 mm height) onto which 0.1 mm platinum foil electrodes [16
generation of diaryliodoniumcompounds performed in an electrochemical microreactor (30 mA) at a flow rate of 80 µL/min (residence time: 17 s) at 25 °C.
Acknowledgements
We thank Prosidion Ltd and Chemistry Innovation/EPSRC for generous support and the EPSRC National Mass Spectrometry Service Centre
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Graphical Abstract
Scheme 1:
Electrochemically generated N-acyliminium ions 1 and subsequent reactions.